Complete bibliography of Harrington lab publications can be found here.

 

SELECTED PAST 10 YEARS

Benslimane Y, Sánchez-Osuna M, Coulombe-Huntington J, Bertomeu T, Henry D, Huard C, Tyers M, Harrington L. (2021) A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition. Aging Cell, Apr;20(4):e13331. doi: 10.1111/acel.13331. Epub 2021 Mar 4.

Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papodopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington L. (2020) Genome-wide screens reveal that resveratrol induces replicative stress in human cells, Mol. Cell, 79(5):846-858. See also accompanying highlight in Mol Cell: Clarke TL and Mostoslavsky R. (2020) Resveratrol: friend or foe? doi: 10.1016/j.molcel.2020.07.010.

Criqui M, Chu TW, Qamra A, Sharma M, Henry D, Barsyte D, Arrowsmith CH, Winegarden N, Lupien M, Harrington L. (2020) Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment, eLife, Apr 16;9. pii: e47333. doi: 10.7554/eLife.47333.

Harrington L, Baird DM. (2020) Editorial overview: The instability of the cancer genome: it starts at the end. Curr Opin Genet Dev. Mar 30 2020, epub ahead of print. pii: S0959-437X(20)30025-3. doi: 10.1016/j.gde.2020.02.020.

Harrington L and Pucci F. (2018) In medio stat virtus: unanticipated consequences of telomere disequilibrium. Phil Trans Roy Soc Lon B. Mar 5; 373(1741). doi: 10.1098/rstb.2016.0444.

Fairlie J, Holland R, Pilkington J, Pemberton J, Harrington L, Nussey DH. (2016) Lifelong leukocyte telomere dynamics and survival in a free-living mammal. Aging Cell. Feb;15(1):140-8. doi: 10.1111/acel.12417.

Fairlie J and Harrington L. (2015) Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation. DNA Repair 25C:54-59. doi: 10.1016/j.dnarep.2014.11.005.

Pucci F, Gardano L, and Harrington, L. (2013) Short telomeres in ESCs lead to unstable differentiation, Cell Stem Cell, 12:479-486. See highlight in Cell Stem Cell: Allsopp R. (2013) Short telomeres flirt with stem cell commitment, Cell Stem Cell 12(4)383-384. doi: 10.1016/j.stem.2013.01.018.

Wong LH, Unciti-Broceta A, Spitzer M, White M, Tyers M, and Harrington L. (2013). A yeast chemical genetic screen identifies inhibitors of human telomerase, Chemistry & Biology, 20:333-340. doi: 10.1016/j.chembiol.2012.12.008.

Gardano L, Pucci F, Christian L, Le Bihan T, Harrington L. (2013) Telomeres, a busy platform for cell signaling, Front Oncol. 3:146. doi: 10.3389/fonc.2013.00146.

Patton EE and Harrington L. (2013) Cancer: trouble upstream, Nature 320-321. doi: 10.1038/495320a.

Gardano L, Holland L, Oulton R, LeBihan T, Harrington L. (2012) Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin. Nucl Acids Res, 2012; 40(5):e36. doi: 10.1093/nar/gkr1243.

Taboski M, Sealey D, Dorrens J, Tayade C, Betts D, Harrington L. (2012) Long telomeres bypass the requirement for telomere length maintenance in human tumorigenesis. Cell Reports, 1:91-98. doi: 10.1016/j.celrep.2011.12.004.